Singlet-triplet splittings in free and self-trapped excitons

We discuss the available experimental data for the singlet-triplet splitting of free and self-trapped excitons in alkali halides. These data are analysed quantitatively using the pseudopotential method of Bartram, Stoneham and Gash. The predictions confirm the trend emerging from the observed data, namely that the splittings are systematically lower for the self-trapped systems. This difference comes principally from the spread of the self-trapped hole onto two ions, and would not be expected, for example, if the hole were localised on a single site

Diabetic complications and their implications on health care in Asia.

Diabetes mellitus is a growing health problem in the Asia-Pacific region. The acute and chronic complications of diabetes mellitus are major causes of hospital admissions, blindness, renal failure, amputations, stroke, and coronary heart disease in this region. Compared with the general population, the annual per capita health care expenditure is estimated to be four-fold for people with diabetes. Recent prospective studies have provided unequivocal evidence for the crucial role of prolonged hyperglycaemia in the development of chronic diabetic complications. Although the aetiology of hyperglycaemia-induced damage of the kidneys, eyes, nerves, and arteries still remain to be elucidated, observational and interventional studies show that the occurrence and progression of these complications can be prevented by the optimal control of blood glucose, hypertension, and dyslipidaemia. Lifestyle changes such as weight control, increased physical exercise, and smoking cessation are also potentially beneficial in preventing diabetes mellitus and coronary artery disease. Furthermore, the morbidity and mortality caused by diabetes mellitus can be reduced by secondary prevention through regular screening, early detection, and appropriate treatment of chronic complications. Improved diabetes education is needed among health professionals as well as the general and diabetic populations. Government and public health officials should be mindful of the economic impact of this major health problem so that adequate health care resources can be allocated for the primary and secondary prevention of diabetic complications.published_or_final_versio

Gastrointestinal bleeding in patients on novel oral anticoagulants: Risk, prevention and management

Novel oral anticoagulants (NOACs), which include direct thrombin inhibitor (dabigatran) and direct factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), are gaining popularity in the prevention of embolic stroke in non-valvular atrial fibrillation as well as in the prevention and treatment of venous thromboembolism. However, similar to traditional anticoagulants, NOACs have the side effects of bleeding, including gastrointestinal bleeding (GIB). Results from both randomized clinical trials and observations studies suggest that high-dose dabigatran (150 mg b.i.d), rivaroxaban and high-dose edoxaban (60 mg daily) are associated with a higher risk of GIB compared with warfarin. Other risk factors of NOAC-related GIB include concomitant use of ulcerogenic agents, older age, renal impairment, Helicobacter pylori infection and a past history of GIB. Prevention of NOAC-related GIB includes proper patient selection, using a lower dose of certain NOACs and in patients with renal impairment, correction of modifiable risk factors, and prescription of gastroprotective agents. Overt GIB can be managed by withholding NOACs followed by delayed endoscopic treatment. In severe bleeding, additional measures include administration of activated charcoal, use of specific reversal agents such as idarucizumab for dabigatran and andexanent alfa for factor Xa inhibitors, and urgent endoscopic management.published_or_final_versio

Quality-of-service routing with two concave constraints

Routing is a process of finding a network path from a source node to a destination node. A good routing protocol should find the "best path" from a source to a destination. When there are independent constraints to be considered, the "best path" is not well-defined. In our previous work, we developed a line segment representation for Quality-of-Service routing with bandwidth and delay requirements. In this paper, we propose how to adopt the line segment when a request has two concave constraints. We have developed a series of operations for constructing routing tables under the distance-vector protocol. We evaluate the performance through extensive simulations. ©2008 IEEE.published_or_final_versio

A comparative study of the quality of life of patients with advanced chronic obstructive pulmonary disease and terminal cancer

2005-2006 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Neuroeconomics of health care financing options: willingness to pay and save

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Psychosocial risk factors associated with falls among Chinese community-dwelling older adults in Hong Kong

This study examined the relationship between psychosocial factors and falls among community-dwelling older adults in the Hong Kong Special Administrative Region of China. The study included 1573 adults aged 60 or above who lived at home and who were applying for long-term care services. These participants were part of a large cross-sectional survey carried out between 2003 and 2004 in which they completed the Hong Kong Chinese version of the Resident Assessment Instrument-Home Care (RAI-HC) assessment. Of those persons who were surveyed, 516 (32.8%, 95% CI 30.5% to 35.2%) had fallen in the previous 90 days. Bivariate analyses showed that five psychosocial factors (depressive symptoms, fear of falling, a decline in social activities, the number of hours of informal care support during weekdays and living alone) were significantly associated with falls (. P <. 0.05). Logistic regression analysis showed living alone (odds ratio (OR) = 0.62; 95% CI 0.44 to 0.86) was the only psychosocial factor significantly associated with falls, after adjusting for the known significant factors related to falls. It was also found that more elders who lived with others had environmental hazards than those who lived alone (71.0% vs 29.0%, 2 = 4.80, . P = 0.028). These findings suggested that living with others may not be as safe as we assume. Interventions to increase awareness of home safety and to seek co-operation with family members in falls prevention are recommended. Fall preventive strategies should be educated to family members who are living with frail older adults. On the other hand, Chinese older adults who live alone often receive support from relatives or friends. Social support seems to be crucial to prevent them from falls and this measure is recommended to be continued in the community. © 2010 Blackwell Publishing Ltd.postprin

Performance Analysis of Quantization-Based Approximation Algorithms for Precomputing the Supported QoS

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Approximation algorithm for QoS routing with multiple additive constraints

In this paper, we study the problem of computing the supported QoS from a source to a destination with multiple additive constraints. The problem has been shown to be NP-complete and many approximation algorithms have been developed. We propose a new approximation algorithm called multi-dimensional relaxation algorithm. We formally prove that our algorithm produces smaller approximation error than the existing algorithms. We further verify the performance by extensive simulations. ©2009 IEEE.published_or_final_versio

Emission mechanism of GeV-quiet soft gamma-ray pulsars: a case for peculiar geometry?

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